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  • Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis - WebMD
    About 1 in 17,000 people are born with a genetic disease called adrenoleukodystrophy (ALD) This severe brain disorder mainly affects boys and men There’s no cure yet for it, but a diagnosis
  • Adrenoleukodystrophy (ALD) - Johns Hopkins Medicine
    What is ALD? Adrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord Myelin acts as insulation around the nerve fibers
  • Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic
    In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your brain, nervous system and adrenal gland The most common type of ALD is X-linked ALD, which is caused by a genetic defect on the X chromosome
  • ALD: Adrenoleukodystrophy, Disease, X-Linked - Cleveland Clinic
    Adrenoleukodystrophy (ALD) is a genetic disorder It affects the nervous system and adrenal glands ALD symptoms include behavioral changes
  • Adrenoleukodystrophy (ALD) - Boston Childrens Hospital
    Adrenoleukodystrophy (ALD) is a rare genetic condition that affects males and females differently In childhood, boys are primarily affected Girls are not typically affected, though they may develop symptoms as adults
  • Adrenoleukodystrophy - United Leukodystrophy Foundation
    Adult cerebral ALD is relatively rare, only representing approximately 3% of all ALD cases Age of onset varies from the twenties to the fifties The symptoms are similar to those of schizophrenia with dementia, and the progression of the disorder is rapid
  • Facts about ALD - Adrenoleukodystrophy
    Adrenoleukodystrophy (ALD) is a genetic disorder that affects the adrenal glands, spinal cord, and the white matter of the brain It is severe and progressive The disorder was first identified in 1923 and was formerly known as Schilder’s disease and sudanophilic leukodystrophy
  • What is ALD? - ALD Alliance
    Adrenoleukodystrophy, or ALD, is a deadly genetic disease that affects 1 in 17,000 people As it is an X-linked genetic disease, which means, it most severely affects boys and men ALD involves multiple organs in the body, but most prominently affects the brain and spinal cord
  • What is Adrenoleukodystrophy (ALD)? - Navigating ALD
    ALD is caused by an underlying genetic mutation in the ABCD1 gene, which affects the body’s ability to create the protein that helps the process of breaking down very long–chain fatty acids (VLCFAs) A buildup of VLCFAs can cause adrenal problems and can potentially lead to brain damage





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