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  • The Pharmacokinetics of Levetiracetam in Critically Ill Adult . . . - MDPI
    Fourteen critically ill patients in an intensive care unit were enrolled in the study and received intravenous levetiracetam Blood samples were collected at specific time points to determine the levetiracetam pharmacokinetics
  • Analysis of the clinical characteristics of the liver injury induced by . . .
    Levetiracetam (LEV) has a low risk of hepatotoxicity due to low liver metabolism Knowledge regarding the association between LEV exposure and liver injury is based mainly on case reports The purpose of this study is to summarize the clinical features of LEV-induced liver injury
  • Review
    Levetiracetam (LEV) is an antiseizure medication (ASM) whose mechanism of action involves the modulation of neurotransmitters release through binding to the synaptic vesicle glycoprotein 2A It is a broad-spectrum ASM displaying favorable pharmacokinetic and tolerability profiles
  • Article 731
    Following oral administration of twice-daily dosing for 10 days, total body clearance decreased by 38% and the half-life was 2 5 hours longer in the elderly compared to healthy adults
  • Neuropharmacology of Levetiracetam as Anti-epileptic Medication
    This review describes the rationale for the discovery and preclinical profile of brivaracetam (BRV), currently under regulatory review as adjunctive therapy for adults with partial-onset
  • Anti-seizures therapeutics in patients with epilepsy: an approach to . . .
    In this review, we present the latest reports on the effectiveness of levetiracetam and its potential in the treatment of epilepsy in children and adults
  • Levetiracetam, from broad-spectrum use to precision . . . - Seizure
    This narrative review analyzes the current evidence related to the use of LEV for the treatment of seizures Illustrative clinical scenarios and practical decision-making approaches are also addressed, therefore aiming to define a rational use of this ASM
  • Severe drug-induced liver injury caused by levetiracetam – A case . . .
    Levetiracetam (LEV) is a broad-spectrum, second-generation anti-seizure medication, which has quickly become one of the most commonly prescribed drugs for people with epielpsy due to its good tolerability, rapid up-dosing capability, with both parenteral and enteral routes of administration
  • Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of . . .
    Systematic Review: The authors reviewed the literature using traditional sources (e g , PubMed) and databases (e g , ClinicalTrials gov) to assess the status of levetiracetam (LEV) in clinical trials for Alzheimer's disease (AD) and in preclinical studies in animal models





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