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  • Alnylam® Pharmaceuticals
    Learn about Alnylam Pharmaceuticals, RNAi therapeutics, and the company's efforts in treating amyloidosis, hyperoxaluria, and porphyria
  • Investor Relations | Alnylam Pharmaceuticals, Inc.
    The Investor Relations website contains information about Alnylam Pharmaceuticals, Inc 's business for stockholders, potential investors, and financial analysts
  • Alnylam Corporate Fact Sheet - Alnylam Pharmaceuticals
    Product Pipeline From science to medicine, bench to bedside, possibility to patient, Alnylam has advanced RNAi therapeutics from raw, groundbreaking,
  • Careers - Alnylam Pharmaceuticals
    CAREERS AT ALNYLAM This Is YOUR Moment This is the moment when you decide you want to be part of what's next rather than what is The moment when you add your experience and skills to a team that has pioneered RNA interference (RNAi) therapeutics – an entirely new class of medicines that is reshaping the way that medicine treats disease
  • Clinical Development Pipeline | Alnylam® Pharmaceuticals
    Alnylam is at the forefront of RNAi therapeutics with a robust pipeline of investigational medicines Learn about Alnylam's pipeline of products in clinical development
  • Early Stage RNAi Therapeutics Pipeline - Alnylam
    8 Alnylam Early Stage Clinical Development and 2020 IND Pipeline 1 POC, proof of concept –defined as having demonstrated target gene knockdown and or additional evidence of activity in clinical studies 2 Cemdisiran is currently in Phase 2 development and pozelimab is currently in Phase 1 development; Alnylam and Regeneron are evaluating potential combinations of these two investigational
  • How RNAi Works | Alnylam® Pharmaceuticals
    How siRNA Work When the siRNA duplex is delivered into the cell, it is recognized by a protein complex known as the RNA-induced silencing complex (RISC), which already resides in the cell as a primary component of the natural RNAi pathway Our siRNA duplex is recognized by and loaded into RISC, which removes one of the two strands (the “passenger” strand)
  • Our Products - Alnylam Pharmaceuticals
    Find information about Alnylam's pharmaceutical products: ONPATTRO® (patisiran), GIVLAARI® (givosiran), OXLUMO® (lumasiran), and AMVUTTRA® (vutrisiran)
  • Alnylam is Leading the RNAi Revolution - Alnylam Pharmaceuticals
    Alnylam has pioneered RNA interference (RNAi) therapeutics, an innovative class of medicines that’s disrupting disease Alnylam was founded in 2002 to harness the breakthrough discovery of RNAi to
  • About Alnylam® Pharmaceuticals
    ALNYLAM IS LEADING THE RNAi REVOLUTION™ Alnylam is a leading independent biopharmaceutical company and the pioneer in RNA interference (RNAi) therapeutics – a revolutionary approach to treating diseases which “silences” the genes that cause or contribute to them Founded in 2002 by a group of distinguished researchers and biotech leaders, Alnylam’s work over more than two decades





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